PS The Goods® - Our Articles + Blogs
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Can NAD+ support energy during perimenopause?
NAD+ supplementation supports cellular energy production through the mitochondrial pathway, which is directly relevant to the fatigue and cognitive symptoms many women experience during perimenopause.† The perimenopausal transition places increased demand on cellular energy systems at exactly the life stage when NAD+ levels are already declining with age, creating a compounding gap that supplementation can help address.† learn more.
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Why does energy drop in your 30s and 40s? And can NAD+ help?
The energy decline many women experience in their 30s and 40s has a cellular explanation: NAD+ levels, which power mitochondrial energy production in every cell, begin declining measurably from the mid-30s onward.† Research published in Nutrients via the National Institutes of Health documents that NAD+ bioavailability declines during normal aging, with high cellular NAD+ levels associated with metabolic and mitochondrial health. Learn more.
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NR vs NMN: which is better for women?
Both NR (nicotinamide riboside) and NMN (nicotinamide mononucleotide) are NAD+ precursors: compounds the body converts into NAD+ intracellularly because NAD+ itself cannot be absorbed intact from supplements. Learn more about what sets them apart, and which is best for you.
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What's the best NAD+ supplement for women?
The best NAD+ supplement for women delivers a clinically studied dose of nicotinamide riboside (NR), the most researched bioavailable NAD+ precursor, in a clean formula without unnecessary additives. NAD+ is a coenzyme present in every living cell that plays a central role in cellular energy production, DNA repair, and healthy aging.† NAD+ levels decline naturally with age, with measurable decreases beginning in the 30s, making supplementation increasingly relevant for women in their mid-30s and beyond.
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Creatine + Brain Function: What does the research say?
Creatine supports brain energy metabolism through the same phosphocreatine-ATP system it uses in muscle tissue, and research suggests it may improve memory and cognitive performance, particularly under conditions of fatigue, sleep deprivation, or metabolic stress.† Women start with significantly lower creatine stores than men, and those stores decline further with age and during the hormonal shifts of perimenopause, making supplementation especially relevant for women experiencing brain fog or mental fatigue.
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Creatine + Perimenopause: What does research say?
Creatine does not treat perimenopause, but research suggests it supports several of the systems most affected by the perimenopausal transition: muscle energy, lean mass preservation, bone density, and cognitive function.† Women in perimenopause experience a natural decline in creatine stores alongside the hormonal shifts of this life stage, and daily supplementation with 5 grams of creatine monohydrate may help address that gap.†
