· By Amy Suzanne Upchurch, Founder + CEO of Pink Stork, Certified Health Coach, INHC
What actually happens in your body when you're stressed?
What actually happens in your body when you're stressed?
When you're stressed, your hypothalamus signals your adrenal glands to release cortisol and adrenaline, which raise your heart rate, sharpen alertness, and temporarily redirect energy away from digestion and other non-urgent functions. This response is designed to be short-lived: once the perceived threat passes, hormone levels are supposed to drop back down. The problem for a lot of women is not the stress response itself, it's that it stays switched on far longer than it was built to, because the stressors driving it (deadlines, kids, financial pressure) don't resolve the way a single acute threat would.
The stress response, step by step
According to Mayo Clinic, a perceived threat triggers the hypothalamus, a small region at the base of the brain, to set off a hormonal alarm system. This prompts the adrenal glands to release a surge of hormones, including cortisol and adrenaline, which increase heart rate and blood pressure and sharpen focus. Once the threat passes, cortisol and adrenaline are supposed to drop and the body returns to baseline.
What happens when the stress response doesn't turn off
Chronic stress keeps this system activated for far longer than it was designed for. Mayo Clinic notes that long-term activation of the stress-response system and the resulting overexposure to cortisol and other stress hormones can disrupt almost all of the body's processes, contributing to issues like headaches, poor sleep, and elevated risk for several chronic health conditions.
Why this system doesn't work the same for everyone
Research on the hypothalamic-pituitary-adrenal (HPA) axis, the system driving this response, has found consistent sex-based differences in how it activates and resolves, though the direction and size of those differences vary depending on the type of stressor and hormonal context. Much of the foundational research on the stress response was conducted primarily in male subjects, which is part of why women's experience of stress has historically been underexplained. We cover this in more depth in our guide on why stress affects women differently than men.
Supporting a healthy stress response day to day
This isn't about eliminating stress, since some level of stress response is a normal and necessary part of how the body functions.† It's about supporting your body's ability to return to baseline rather than staying activated. Adaptogens like ashwagandha have been studied for their role in supporting a healthy stress response, and Cortisol Complex combines 300 mg of organic ashwagandha with chamomile, saffron, and a full B-vitamin complex for this purpose.† Cortisol Complex, designed for women navigating high-stress seasons, is formulated to support a balanced mood and steady energy throughout the day.†
"Focus on total and holistic health where we're thinking about all these things in congruency with one another."
— Dominique Landry, Founder of Fit Enough
What this looks like day to day
- Notice when stress has become constant rather than occasional
- Prioritize sleep, since poor sleep and stress reinforce each other
- Consider adaptogen-based support formulated for daily stress resilience, alongside foundational habits, not instead of them
- Talk to your provider if stress is affecting your sleep, mood, or daily functioning in a persistent way
If pregnancy or postpartum is part of your current season, Cortisol Complex is breastfeeding-friendly per its product page, though you should still consult your healthcare provider before starting any new supplement while pregnant or breastfeeding.
Cortisol Complex is third-party tested in cGMP-certified laboratories and formulated to be vegan, non-GMO, and gluten-free.
For a deeper look at the specific patterns of stress physiology, see our guides on why you crash in the afternoon, what the ashwagandha research actually shows, and what the saffron research says about mood.
Frequently asked questions
Is stress always bad for you?
No. A short-term stress response is a normal, healthy function. The concern is chronic activation that doesn't resolve, according to Mayo Clinic.
Can supplements lower my cortisol?
No supplement works like a dial that lowers cortisol on command. Research on ingredients like ashwagandha has found associations with supporting a healthy stress response, which is a different claim than directly controlling a biomarker.
Why does stress affect sleep so much?
Cortisol and sleep are closely linked, since cortisol follows a daily rhythm that is supposed to decline toward bedtime. Chronic stress can disrupt that pattern.
Do men and women experience stress the same way?
Research has found consistent differences in how the HPA axis functions by sex, though the direction of those differences varies by study and context. See our full guide on this topic for more detail.
Is Cortisol Complex safe during pregnancy?
Cortisol Complex is not formulated for use during pregnancy.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement, especially during pregnancy, breastfeeding, or while managing a medical condition. Keep out of reach of children.