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By Amy Suzanne Upchurch, Founder + CEO of Pink Stork, Certified Health Coach, INHC

What are the signs of iron deficiency in women, and how do you know for sure?

The signs of iron deficiency in women include fatigue, brain fog, dizziness, irritability, restless legs, and unusual cravings for things like ice, but the only way to know for sure is a ferritin blood test, not a symptom checklist. Iron deficiency without anemia affects roughly 38 percent of nonpregnant, reproductive-age women in high-income countries, according to a 2025 JAMA review, which means a large share of women experiencing these symptoms have never had their iron status actually checked. Guessing which supplement will fix fatigue skips the one step that actually answers the question.

Always consult your healthcare provider before starting any new supplement, especially during pregnancy, breastfeeding, or while managing a medical condition.

Why women are especially vulnerable to iron deficiency

Menstruation is the single biggest reason iron deficiency is so common in reproductive-age women. Regular blood loss each cycle creates an ongoing iron demand that diet alone does not always meet, and pregnancy increases that demand further. According to a 2025 JAMA review of iron deficiency in adults, the most common causes of iron deficiency are menstrual and gastrointestinal blood loss, impaired absorption, inadequate dietary intake, and pregnancy, with iron deficiency affecting up to 84 percent of pregnant women in high-income countries by the third trimester.

What symptoms actually look like

Iron deficiency does not always announce itself as "tired." According to Mayo Clinic, symptoms of iron deficiency anemia can include extreme tiredness, headache or lightheadedness, cold hands and feet, brittle nails, restless legs syndrome, and unusual cravings for non-food items such as ice or dirt, a symptom called pica.

  • Fatigue that does not improve with sleep
  • Brain fog or difficulty concentrating
  • Dizziness or lightheadedness
  • Restless legs, especially at night
  • Cravings for ice, dirt, or other non-food items (pica)
  • Cold hands and feet, brittle nails

Why a ferritin test matters more than guessing

Ferritin is the blood marker that reflects your body's stored iron, and it is the test that answers the question a symptom list cannot. According to Cleveland Clinic, iron-deficiency anemia is diagnosed through blood testing, not through symptoms alone, since fatigue and related symptoms overlap with many other causes. If you are experiencing these symptoms, ask your provider for a ferritin check before assuming any single supplement will resolve them.

Where a prenatal fits into this picture

Total Prenatal is formulated with iron bisglycinate to support healthy iron status as part of a preconception or pregnancy routine.† It is not positioned as a standalone fix for fatigue, since fatigue has many possible causes and iron status should be confirmed through testing, not assumed.† Total Prenatal, a 22-nutrient blend with ScentCert technology, is one part of a broader approach that starts with knowing your numbers.

"I think so many things can be avoided if there's just prevention."

— Dr. Samantha Ess, ND, Naturopathic Doctor specializing in hormone health and fertility

"Motherhood taught me that exhaustion is not something to just push through and pray away. It is something to investigate. Ask your provider for the numbers. Knowing is always better than guessing."

— Amy Suzanne Upchurch, Founder and CEO of Pink Stork

Pink Stork's full product line is third-party tested at ISO 17025 accredited labs, manufactured in cGMP-certified facilities, and carries more than 50,000 verified Amazon reviews.

For more on prenatal absorption and tolerability, see our guide on what makes a prenatal vitamin easier to absorb, and if digestive tolerance is part of your concern, see why some iron supplements upset your stomach more than others.

Frequently asked questions

How common is iron deficiency in women?

Roughly 38 percent of nonpregnant, reproductive-age women in high-income countries have iron deficiency without anemia, according to a 2025 JAMA review, and the rate is even higher during pregnancy.

What test checks for iron deficiency?

A ferritin blood test measures your body's stored iron and is the standard way to confirm iron deficiency, rather than relying on symptoms alone.

Can iron deficiency cause brain fog?

Difficulty concentrating is a commonly reported symptom of iron deficiency, alongside fatigue, dizziness, and restless legs, according to a 2025 JAMA review.

Should I take an iron supplement if I feel tired?

Talk to your provider and ask about a ferritin test first. Fatigue has many possible causes, and confirming iron status helps determine whether iron supplementation is the right approach for you.

Is Total Prenatal a treatment for fatigue?

No. Total Prenatal supports healthy iron status as part of a preconception or pregnancy routine, but it is not positioned as a standalone fix for fatigue.†

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement, especially during pregnancy, breastfeeding, or while managing a medical condition. Keep out of reach of children.