· By Amy Suzanne Upchurch, Founder + CEO of Pink Stork, Certified Health Coach, INHC
Does menopause affect your memory and brain health?
Yes. Research reviewed in The Lancet Obstetrics, Gynaecology, and Women's Health found that more than two-thirds of women report difficulties with memory or concentration during the menopause transition, yet these cognitive symptoms remain poorly recognized and under-researched. Menopause is often framed as a purely reproductive event, but the evidence points to it also being a significant brain event. Understanding that connection is the first step toward taking cognitive changes seriously instead of dismissing them.
Why brain fog during menopause is real, not "just stress"
Researchers at UCL and Monash University, publishing a major review in The Lancet, found that forgetfulness, reduced concentration, and brain fog are common during the menopause transition, with more than two-thirds of women reporting these symptoms.[1] The review notes that hormonal changes, sleep disturbances, and psychological stress can all contribute, but that overall cognitive performance for most women experiencing this brain fog remains within expected ranges, not a sign of dementia.[1]
Mayo Clinic's Dr. Juliana Kling has described brain fog during menopause as a real, recognized phenomenon that often brings relief once women understand it isn't a sign of something more serious.[2]
Why this matters more for women specifically
The stakes of understanding menopause-related brain changes go beyond day-to-day forgetfulness. Almost two-thirds of Americans living with Alzheimer's disease are women, and researchers increasingly point to the midlife menopausal transition, not just longer lifespan, as part of the explanation.[3] Stanford Medicine neurologists note that while longevity differences account for much of the disparity, the biological role of the menopause transition in brain aging is an active and important area of research.[4]
"Women are armed with a ton of information. They just may not know how does this apply to me?"
— Jessica Nazzaro, DO, FACOG, NCMP, Board-Certified OB-GYN and National Certified Menopause Practitioner
What actually helps cognitive symptoms during menopause
Because menopause-related cognitive symptoms are driven by multiple overlapping factors, hormonal changes, sleep disruption, and stress, support strategies tend to work best when they address the whole picture rather than a single mechanism.
A research angle most creatine content misses
Creatine is typically marketed around strength and athletic performance, but a growing body of research looks specifically at its role in cognitive function, including in women during the menopause transition. A systematic review and meta-analysis found that creatine supplementation may significantly affect processing speed in women specifically, suggesting sex-specific cognitive effects that general creatine research has historically overlooked.
Creatine Monohydrate, designed to support strength, energy, and cognitive function, is a single-ingredient, micronized powder with no added sweeteners or fillers, formulated specifically for women.† It's third-party tested in cGMP-certified laboratories and vegan, non-GMO, and gluten-free.
Supporting your foundation alongside your provider's guidance
Our micronized creatine with just one ingredient is meant to be one part of a broader approach to menopause-related cognitive support, alongside sleep, stress management, and any care plan your provider recommends. It is not a treatment for menopause, brain fog, or any cognitive condition.
"For too long, women have been told to just push through the fog. I believe our minds deserve the same serious attention as any other part of our health, and that conviction, grounded in faith and backed by science, shapes how we build every formula."
— Amy Suzanne Upchurch, Founder and CEO of Pink Stork
A foundational approach to cognitive support during menopause
- Prioritize consistent, quality sleep, since sleep disruption is one of the most common contributors to brain fog during menopause
- Talk to your provider about whether hormone therapy or other treatments are appropriate for your specific symptoms
- Consider strength training paired with a single-ingredient creatine supplement as part of a broader cognitive and physical health routine†
- Track your symptoms so you can describe patterns to your provider, rather than a single bad day
For a closer look at the creatine-specific research, see our companion guide, can creatine help with brain fog during perimenopause.
Frequently asked questions
Is brain fog during menopause a sign of dementia?
No. Research indicates that cognitive performance for most women experiencing menopause-related brain fog remains within expected ranges, and it is not considered a sign of dementia or cognitive decline.
How common is brain fog during menopause?
A major review found that more than two-thirds of women report memory or concentration difficulties during the menopause transition.
What causes menopause-related brain fog?
Researchers point to a combination of hormonal changes, sleep disturbances, and psychological or psychosocial stress, rather than a single cause.
Can creatine really help with menopause-related cognitive changes?
Some research suggests creatine supplementation may support cognitive function, including processing speed, in women.† It is not a treatment for menopause symptoms, and results vary by individual.
Should I talk to my doctor about brain fog during menopause?
Yes. While common, brain fog during menopause is still worth discussing with your provider, especially if it's affecting your daily function or you have concerns about your cognitive health.
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement, especially during pregnancy, breastfeeding, or while managing a medical condition. Keep out of reach of children.