What actually helps with nausea in early pregnancy?

Two of the best-studied options are vitamin B6 and ginger, and head-to-head research shows they perform comparably for most women, each  easing nausea compared to before treatment. The American College of Obstetricians and Gynecologists lists vitamin B6, alone or with doxylamine, as first-line pharmacologic therapy, and ginger as a nonpharmacologic option shown to ease nausea. Neither is a guarantee, and what works can vary from one pregnancy to the next. 

Always consult your healthcare provider before starting any new supplement, especially during pregnancy.

What the head-to-head research actually shows

A randomized clinical trial published in ISRN Obstetrics and Gynecology compared vitamin B6 (40 mg twice daily) directly against ginger (250 mg four times daily) in pregnant women with nausea. Both treatments easing nausea and vomiting symptom scores from baseline, with no statistically significant difference between the two groups.

An earlier trial in the Journal of the Medical Association of Thailand found a similar pattern: both ginger and vitamin B6 significantly eased nausea scores compared to baseline, again with no statistically significant difference between the two treatments. Other trials in this body of research have found ginger slightly outperforming B6 on some measures, so the honest summary is that both are reasonable, evidence-supported first options, not that one clearly beats the other.

What the official guidelines recommend

According to ACOG's practice bulletin on nausea and vomiting of pregnancy, vitamin B6, alone or combined with doxylamine, is considered first-line pharmacologic therapy, while ginger is recommended as a nonpharmacologic option shown to help ease nausea. ACOG also notes that starting treatment early, rather than waiting for symptoms to worsen, may help prevent progression to more severe cases.

Practical ways to use both

• Small, frequent meals and bland or dry foods, per ACOG's dietary guidance
• Ginger in the form that is easiest for you to tolerate: lozenges, tea, capsules, or fresh ginger
• Vitamin B6 taken consistently rather than only reactively, since trials dosed it multiple times daily
• Tracking what helps for you specifically, since individual response varies between the two

"One of the challenges in pregnancy is building that trust... and feeling heard."

— Dr. Tosin Odunsi, MD, MPH, FACOG, Obstetrics and Gynecology Physician

How Nausea Sweets fits in

Nausea Sweets combines active ginger or peppermint oil with vitamin B6 in one organic lozenge, formatted to help ease occasional upset stomach, morning sickness, indigestion, and feelings of bloat.† They come individually wrapped, so they travel easily in a bag, car, or desk drawer for whenever nausea hits. You can read more about our organic ginger and vitamin B6 nausea lozenges, available in Sweet Peppermint, Ginger Mango, and Ginger Raspberry.

Pairing nausea support with foundational prenatal nutrition matters too. Pink Stork's Total Prenatal, formulated for first-trimester sensitivity, includes ScentCert technology specifically to help ease scent-triggered nausea.

"My own first pregnancy was genuinely difficult, and I remember how isolating it felt when nausea was dismissed as something to just push through. That is part of why Nausea Sweets exists: real support you can actually carry with you, not just advice to tough it out."

— Amy Suzanne Upchurch, Founder and CEO of Pink Stork

Trust signals worth knowing

• Nausea Sweets is USDA Organic and third-party tested
• Pink Stork has more than 50,000 verified Amazon reviews across the brand

Related reading

• What causes digestive discomfort when you change how you eat?
• Why does gentle iron matter in a prenatal vitamin?

Frequently asked questions

Is ginger or vitamin B6 more effective for morning sickness?

Research directly comparing the two generally finds them similarly effective, though results vary slightly by study. Both are reasonable first options to discuss with your provider.

How much ginger is safe during pregnancy?

Studies have used doses in the range of 250 mg several times daily up to about 1 gram per day. Confirm the right amount for you with your healthcare provider.

When should nausea and vomiting during pregnancy be treated as more serious?

If you cannot keep liquids down, show signs of dehydration, or your symptoms begin after 9 weeks of pregnancy rather than before, contact your provider, since these can indicate something other than typical morning sickness.

Can I take Nausea Sweets alongside my prenatal vitamin?

Yes, Nausea Sweets is designed to be used alongside your regular prenatal routine. Always consult your healthcare provider about your full supplement routine during pregnancy.

Do Nausea Sweets replace the need for vitamin B6 or ginger recommended by my doctor?

Nausea Sweets combine ginger or peppermint oil with vitamin B6 in one lozenge, but you should still follow your provider's specific guidance on dosing and treatment for your situation.

Is it normal for morning sickness to last all day?

Despite the name, nausea and vomiting of pregnancy can occur at any time of day, and this is common and expected for many women in the first trimester.

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting any new supplement, especially during pregnancy, breastfeeding, or while managing a medical condition. Keep out of reach of children.